| Insert |
DNA: genomic Insert lengths(kb): 2.299999952316284 Tissue: DNA from mouse/human hybrid CIId cell line Gene product: DNA Segment, single copy [D7S23] Alleles: A1, A1, A1, A1, A2, A2, A2, A2, B1, B2 |
| Comments |
The insert contains a BamHI site. Restriction digests of the clone give the following sizes (kb): HindIII--2.6, 2.3; EcoRI--4.9; SacI--3.1, 1.8; BamHI--4.9. The displayed allele frequencies are derived from a non-CF Caucasian population. The frequencies in CF patients are markedly different. Subcloned from the cosmid cNX.2. |
| References |
Estivill X, et al. A candidate for the cystic fibrosis locus isolated by selection for methylation-free islands. Nature 326: 840-845, 1987. PubMed: 2883581
Estivill X, et al. Patterns of polymorphism and linkage disequilibrium for cystic fibrosis. Genomics 1: 257-263, 1987. PubMed: 2895728
Estivill X, et al. Isolation of a new DNA marker in linkage disequilibrium with cystic fibrosis, situated between J3.11 (D7S8) and IRP. Am. J. Hum. Genet. 44: 704-710, 1989. PubMed: 2565082
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